Effect of Bigger Ginger Extract on Reduction of Blood Sugar Rate of Glucose Induced Mice
DOI:
https://doi.org/10.32382/jmak.v14i2.241Kata Kunci:
Bigger Ginger Extract, Blood Sugar, Glucose, Mus MusculusAbstrak
To date, the government and people of Indonesia are still facing health problems. Diabetes, also known as diabetes mellitus, is one of the most common diseases among Indonesians. Some rhizome spices that have antidiabetic potential, one of which is elephant ginger. The purpose of this study was to determine the effectiveness of bigger ginger extract on reducing blood glucose levels in mice. This type of research is an experimental study to determine the effectiveness and concentration of bigger ginger extract on blood glucose levels in mice induced with glucose. Based on the results obtained, Bigger Ginger Rhizome Extract (Zingiber officinale var. Rosc.) has the potential to reduce blood sugar levels in mice with an average reduction value where 5% b/v extract decreased by 48.69%, 10% b/v extract decreased by 50% and 15% b/v extract decreased by 55%. The concentration of 5% b/v in Bigger Ginger Rhizome Extract (Zingiber officinale var. roscoe) shows an optimal reducing effect
Referensi
Afni, N., Said, N., & Yuliet. (2015). Uji Aktifitas Antibakteri Pasta Gigi Ekstrak Biji Pinang (Areca Catechu L.) Terhadap Streptococcus Mutans Dan Staphylococcus Aureus. Galenika Journal Of Pharmacyjournal Of Pharmacy Issn : 2442-8744, 1(March), 48–58.
Barki, T., Kristiningrum, N., Puspitasari, E., & Fajrin, F. A. (2017). Penetapan Kadar Fenol Total Dan Pengujian Aktivitas Antioksidan Minyak Jahe Gajah (Zingiber Officinale Var. Officinale). E-Jurnal Pustaka Kesehatan, 5(3), 432–436.
Dewi, M. K., & Kharisma, Y. (2019). Zingiber Officinale Roscae Water Fraction Effect To Blood Glucose In Mice With High Lipid Die Pengaruh Pemberian Fraksi Air Jahe Gajah ( Zingiber Officinale Rosc . ) Terhadap Kadar Gula Darah Mencit Tua Jantan Yang Diberi Pakan Tinggi Lemak Oleh Iran 30 %. 640–650.
Jannah, N., Saleh, C., & Pratiwi, D. R. (2020). Skrining Fitokimia Ekstrak Etanol Dan Fraksi-Fraksi Daun Alamanda (Allamanda Catharica L.). 81–85.
Leonita, E., & Muliani, A. (2015). Penggunaan Obat Tradisional Oleh Penderita Diabetes Mellitus Dan Faktor-Faktor Yang Berhubungan Di Wilayah Kerja Puskesmas Rejosari Pekanbaru Tahun 2015. 3(1).
Lesmana, H. S., & Broto, E. P. (2019). Profil Glukosa Darah Sebelum, Setelah Latihan Fisik Submaksimal Dan Selelah Fase Pemulihan Pada Mahasiswa Fik Unp. Media Ilmu Keolahragaan Indonesia, 8(2), 44–48. Https://Doi.Org/10.15294/Miki.V8i2.12726
Radiansah, R., & Rahman, N. (2013). Untuk Menurunkan Kadar Gula Darah Pada Mencit Moringa Leaves Extract ( Moringa Oleivera ) As An Alternative To Reduce Blood Sugar Levels On Mice. 2(May), 54–61.
Redi Aryanta, I. W. (2019). Manfaat Jahe Untuk Kesehatan. Widya Kesehatan, 1(2), 39–43. Https://Doi.Org/10.32795/Widyakesehatan.V1i2.463
Rika Afsari, Kusmiyati, I. W. M. (2016). Pengaruh Pemberian Ekstrak Daun Sirih Merah (Piper Crocatum) Terhadap Penurunan Kadar Gula Darah Mencit (Mus Musculus) Rika. 16(1), 49–55.
Rohma, L. N., Rohma, L. N., Sjofjan, O., & Natsir, M. H. (2019). Komposisi Minyak Atsiri Dan Aktivitas Antimikroba Rimpang Temu Putih Dan Jahe Gajah Sebagai Fitobiotik Pakan Unggas. Jurnal Ilmu Dan Teknologi Peternakan Tropis, 6(2), 181.Https://Doi.Org/10.33772/Jitro.V6i2.5560
Setyaningrum, H. D., & Saparinto, C. (2013). Jahe (B. Prasetya W (Ed.); B. Prasety). Penebar Swadaya.
Suharto, I. P. S., Lutfi, E. I., & Rahayu, M. D. (2019). Pengaruh Pemberian Jahe (Zingiber Officinale) Terhadap Glukosa. Ilmiah Ilmu Kesehatan, 7(3), 76–83.
Susanti, N. M. P., Budiman, I. N. ., & Warditiani, N. K. (2015). Skrining Fitokimia Ektrak Etanol 90 % Daun Katuk ( Sauropus Androgynus ( L .) Merr .). Repository Universitas Udayana, 83–86.
S.S, I. P., Nurrahayu, K. I., & Etika, A. N. (2017). The Effect of Ginger ( Zingiber Officinale Roscoe ) Extract to the Number of Neutrophil Cell in Incision Wound of White Rats ( Rattus Norvegicus ). In Advances in Health Sciences Research (Vol. 2, pp. 381–385). Atlantis Press.
Tee, S. A., & Sernita. (2017). Uji Daya Hambat Formula Pasta Gigi Ekstrak Daun Miana ( Coleus Scutellarioides ( L .) Benth ) Terhadap Aktivitas Pertumbuhan Bakteri Streptococcus Mutans. Warta Farmasi, 6(1), 106–114.
Wicaksono, A. P. (2015). Pengaruh Pemberian Ekstrak Jahe Merah (Zingiber Officinale) Terhadap Kadar Glukosa Darah Puasa. Majority, 4(7), 97–102.
Zahrotin, A. (2018). Pengaruh Insulin , Jahe Dan Kombinasi Keduanya Terhadap Jumlah Sel Trofoblas Rattus Norvegicus Model. Qanun Medika, 2(1), 21–28.